Table 5. Univariate and multivariate Cox analysis of 5-year OS in patients with FOS (n=120).
| Characteristics | Total, n | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |||
| Age | 120 | 1.03 (1.02–1.05) | <0.01 | 1.03 (1.02–1.05) | <0.01 | |
| Race | ||||||
| Others | 11 | Reference | ||||
| White | 93 | 0.69 (0.29–1.62) | 0.39 | |||
| Black | 16 | 1.18 (0.43–3.29) | 0.75 | |||
| Sex | ||||||
| Male | 58 | Reference | ||||
| Female | 62 | 0.78 (0.46–1.33) | 0.36 | |||
| SEER stage | ||||||
| Distant | 15 | Reference | Reference | |||
| Localized | 50 | 0.15 (0.07–0.33) | <0.01 | 0.16 (0.07–0.36) | <0.01 | |
| Regional | 55 | 0.19 (0.09–0.40) | <0.01 | 0.24 (0.11–0.53) | <0.01 | |
| Surgery | ||||||
| Yes | 111 | Reference | Reference | |||
| No | 9 | 3.20 (1.51–6.89) | <0.01 | 2.54 (0.86–7.54) | 0.09 | |
| Radiation | ||||||
| Yes | 11 | Reference | Reference | |||
| No | 109 | 0.45 (0.21–0.95) | 0.03 | 0.82 (0.27–2.45) | 0.72 | |
| Chemotherapy | ||||||
| No | 42 | Reference | ||||
| Yes | 78 | 0.79 (0.46–1.38) | 0.41 | |||
OS, overall survival; FOS, fibroblastic osteosarcoma; CI, confidence interval; SEER, Surveillance, Epidemiology, and End Results.