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. 2024 Jul 30;18:1407975. doi: 10.3389/fncel.2024.1407975

Table 2.

Target gene/GAPDH-mRNA abundance.

Target gene Control EAE (2−ΔCt; % of control; statistical difference)
Entpd1 0.01984 ± 0.00208 0.03253 ± 0.00813
(164.0 ± 11.3%, t = 2.52, df = 8, p = 0.0356)
Entpd2 0.03414 ± 0.00107 0.02169 ± 0.0038
(63.5 ± 23.0%, t = 4.87, df = 8, p = 0.0012)
Nt5e 0.01166 ± 0.00200 0.01754 ± 0.00052*
(150.4 ± 24.6%, t = 13.35, df = 8, p < 0.0001)
Ada 0.00237 ± 0.00032 0.00212 ± 0.00057
(t = 0.95, df = 8, p = 0.3571)
Ent1 0.00225 ± 0.00039 0.00225 ± 0.00060
(t = 0.13, df = 8, p = 0.9896)
Ent2 0.00367 ± 0.00032 0.00259 ± 0.00048
(t = 0.13, df = 8, p = 0.9896)
Adora1 0.01563 ± 0.00065 0.01986 ± 0.00513*
(127.1 ± 9.6%, t = 2.63, df = 8, p = 0.0206)
Adora 2a 0.00374 ± 0.00019 0.00333 ± 0.00078
(t = 0.92, df = 8, p = 0.3832)
Adora2b 0.00522 ± 0.00068 0.00412 ± 0.00071
(t = 1.90, df = 8, p = 0.0937)
Adora3 0.00900 ± 0.00128 0.02558 ± 0.0038*
(284.2 ± 72.33%, t = 6.375, df = 8, p = 0.0002)
P2xr2 0.00037 ± 0.00014 0.00030 ± 0.00061
(t = 1.61, df = 8, p = 0.1298)
P2xr4 0.02456 ± 0.00433 0.04073 ± 0.00829*
(165.8 ± 12.3, t = 5.59, df = 8, p < 0.0001)
P2xr7 0.00373 ± 0.00060 0.00375 ± 0.00107
(t = 0.40, df = 8, p = 0.6929)
P2ry1 0.00535 ± 0.00062 0.00484 ± 0.00096
(t = 2.04, df = 8, p = 0.059)
P2ry12 0.00869 ± 0.00162 0.01210 ± 0.00159*
(139 ± 1.9%, t = 4.24, df = 8, p = 0.0007)
Tnfa 0.00055 ± 0.00005 0.00258 ± 0.00147*
(469.1 ± 185.0%, t = 3.78, df = 8, p = 0.0054)
Il1b 0.00053 ± 0.00015 0.00439 ± 0.00236*
(828.3 ± 298.4%, t = 3.19, df = 8, p = 0.0127)
Il6 0.00004 ± 0.00010 0.00024 ± 0.00005*
(600.0 ± 35.7%, t = 3.46, df = 8, p = 0.0085)
Lcn2 0.00007 ± 0.00002 0.00117 ± 0.00050*
(1,671 ± 140.4%, t = 3.40, df = 8, p = 0.0093)
C3 0.02241 ± 0.00369 0.12017 ± 0.02740*
(536.2 ± 180.5%, t = 5.50, df = 8, p = 0.0006)