Table 2.
Target gene | Control | EAE (2−ΔCt; % of control; statistical difference) |
---|---|---|
↑ Entpd1 | 0.01984 ± 0.00208 | 0.03253 ± 0.00813 (164.0 ± 11.3%, t = 2.52, df = 8, p = 0.0356) |
↓ Entpd2 | 0.03414 ± 0.00107 | 0.02169 ± 0.0038 (63.5 ± 23.0%, t = 4.87, df = 8, p = 0.0012) |
↑ Nt5e | 0.01166 ± 0.00200 | 0.01754 ± 0.00052* (150.4 ± 24.6%, t = 13.35, df = 8, p < 0.0001) |
Ada | 0.00237 ± 0.00032 | 0.00212 ± 0.00057 (t = 0.95, df = 8, p = 0.3571) |
Ent1 | 0.00225 ± 0.00039 | 0.00225 ± 0.00060 (t = 0.13, df = 8, p = 0.9896) |
Ent2 | 0.00367 ± 0.00032 | 0.00259 ± 0.00048 (t = 0.13, df = 8, p = 0.9896) |
↑ Adora1 | 0.01563 ± 0.00065 | 0.01986 ± 0.00513* (127.1 ± 9.6%, t = 2.63, df = 8, p = 0.0206) |
Adora 2a | 0.00374 ± 0.00019 | 0.00333 ± 0.00078 (t = 0.92, df = 8, p = 0.3832) |
Adora2b | 0.00522 ± 0.00068 | 0.00412 ± 0.00071 (t = 1.90, df = 8, p = 0.0937) |
↑ Adora3 | 0.00900 ± 0.00128 | 0.02558 ± 0.0038* (284.2 ± 72.33%, t = 6.375, df = 8, p = 0.0002) |
P2xr2 | 0.00037 ± 0.00014 | 0.00030 ± 0.00061 (t = 1.61, df = 8, p = 0.1298) |
↑ P2xr4 | 0.02456 ± 0.00433 | 0.04073 ± 0.00829* (165.8 ± 12.3, t = 5.59, df = 8, p < 0.0001) |
P2xr7 | 0.00373 ± 0.00060 | 0.00375 ± 0.00107 (t = 0.40, df = 8, p = 0.6929) |
P2ry1 | 0.00535 ± 0.00062 | 0.00484 ± 0.00096 (t = 2.04, df = 8, p = 0.059) |
↑ P2ry12 | 0.00869 ± 0.00162 | 0.01210 ± 0.00159* (139 ± 1.9%, t = 4.24, df = 8, p = 0.0007) |
↑ Tnfa | 0.00055 ± 0.00005 | 0.00258 ± 0.00147* (469.1 ± 185.0%, t = 3.78, df = 8, p = 0.0054) |
↑Il1b | 0.00053 ± 0.00015 | 0.00439 ± 0.00236* (828.3 ± 298.4%, t = 3.19, df = 8, p = 0.0127) |
↑ Il6 | 0.00004 ± 0.00010 | 0.00024 ± 0.00005* (600.0 ± 35.7%, t = 3.46, df = 8, p = 0.0085) |
↑Lcn2 | 0.00007 ± 0.00002 | 0.00117 ± 0.00050* (1,671 ± 140.4%, t = 3.40, df = 8, p = 0.0093) |
↑C3 | 0.02241 ± 0.00369 | 0.12017 ± 0.02740* (536.2 ± 180.5%, t = 5.50, df = 8, p = 0.0006) |