Fig. 7.

(a) Typical micro-injection molding processes and six injection-filling methods. (b) (i) Schematic of the MN system loaded with ADSCs and PDGF-D for diabetic wound therapy. (ii) Schematic of the fabrication process of the MNs arrays. (iii) Optical image, Scanning Electron Microscopy (SEM) photo, and fluorescence image of ADSC-PDGF@HAMA-MNs wrapped with fluorescent probe labelling [115]. Adapted reprinted with permission from Ref. [115], License Number: 5,792,350,949,641. Copyright © 2022 Wiley‐VCH GmbH. (c) (i) Fabrication of silk fibroin microneedle patches, (ii) microneedle patch morphology, (iii) contact angle, (iv) morphology of microneedle patches before and after insertion into the rabbit ear scar [116]. Adapted reprinted with permission from Ref. [116], Copyright © 2022 The Authors. Published by American Chemical Society. This publication is licensed under CC-BY-NC-ND 4.0. (d) (i) Schematic of the bilayer dissolving microneedle (BMN) fabrication process, (ii) confocal micrographs and SEM images of fluorescent BMNs, (iii) photograph of skin surface after insertion of BMN [117]. Adapted reprinted with permission from Ref. [117], based on CC-BY–NC–ND License. Copyright © 2021 The Authors.