Table 3. Comparison of the diagnostic performances of CEUS TI-RADS in nodules of different sizes.

Group	SEN (%)	SPE (%)	ACC (%)	PPV (%)	NPV (%)	AUC (95% CI)	Cutoff	P value
All	93.2	75.5	85.2	83.0	89.0	0.898 (0.867–0.924)	5 points	<0.001
A	76.2	75.0	71.0	67.3	80.5	0.795 (0.721–0.857)	6 points	<0.001
B	95.9	88.1	92.8	92.6	93.2	0.949 (0.916–0.971)	5 points	<0.001
C	69.2	92.6	85.0	81.8	86.2	0.801 (0.644–0.910)	5 points	<0.001

The nodules were grouped based on their size as follows: size ≤1 cm, group A; size >1 and ≤4 cm, group B; and size >4 cm, group C. CEUS TI-RADS, contrasted-enhanced ultrasound thyroid imaging reporting and data system; SEN, sensitivity; SPE, specificity; ACC, accuracy; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; CI, confidence interval.