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. 2024 Jul 9;14(8):5473–5489. doi: 10.21037/qims-24-291

Table 2. Comparison the of T1, T2, PD, and ADC values between PCA and benign lesions, between low-risk and intermediate-to-high risk PCA, and between GS upgrade and nonupgrade.

Pathology TZ PZ PCA risk grade TTPB GS ≤3+4
PCA (n=61) BPH (n=96) P PCA (n=117) Inflammation (n=117) P GS ≥4+3 (n=116) GS ≤3+4 (n=62) P Upgraded
(n=18)
Nonupgraded
(n=50)
P
T1 (msec) 1,203.83±121.03 1,339.37±169.41 <0.001 1,270.27±126.12 1,402.80±210.84 <0.001 1,261.52±130.66 1,207.00
(1,137.75, 1,275.25)
0.03 1,192.00
(1,112.00, 1,263.75)
1,287.50
(1,217.25, 1,454.25)
0.007
T2 (msec) 74.15±8.10 80.00
(76.00, 85.00)
<0.001 78.00
(73.00, 82.00)
88.57±13.60 <0.001 77.00
(73.00, 82.00)
73.31±7.49 0.001 73.00
(67.00, 79.00)
78.00
(75.75, 81.25)
0.003
PD (pu) 79.22±3.86 81.00
(80.00, 84.00)
<0.001 81.00
(78.00, 83.00)
83.00
(81.00, 85.00)
<0.001 81.00
(78.50, 84.00)
79.00
(77.00, 81.00)
0.003 79.50
(77.00, 82.00)
83.50
(78.75, 84.25)
0.009
ADC
(×10−6 mm2/s)
599.22±87.23 837.00
(785.50, 907.50)
<0.001 605.74±100.80 888.97±160.24 <0.001 580.94±90.10 634.50
(604.00, 695.75)
<0.001 636.50
(602.75, 695.00)
574.00
(528.75, 629.25)
0.002

Data following a normal distribution are expressed as the mean ± standard deviation. Otherwise, data are expressed as the median (first quartile, third quartile). PD, proton density; ADC, apparent diffusion coefficient; PCA, prostate cancer; GS, Gleason Score; TZ, transformation zone; PZ, peripheral zone; TTPB, transperineal prostate biopsy; BPH, benign prostatic hyperplasia.