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(A) % Inhibition of pRbT821 dose response of 2 in OVCAR-3 cells. Potency of 2 with transient 4 h exposure was similar to constant treatment. Mean IC50 reported ± SEM (B) % growth inhibition dose response measured by Cell Titer-Glo in OVCAR-3 cells. Potency of 2 with transient 4h exposure was similar to constant treatment. Mean IC50 reported ± SEM.
