Table 2. Comparison of mean clinical parameters between control and test sites at baseline, 3 months, and 6 months using Wilcoxon signed rank test.

Variable	Site	N	Mean			SD			Mean Diff			P-value
			BL	3M	6M	BL	3M	6M	BL	3M	6M	BL	3M	6M
PI	Control	17	2.32	1.27	1.81	0.45	0.79	0.69	-0.04	0.01	1.21	0.82	0.95	<0.001*
	Test	17	2.37	1.25	0.6	0.49	0.56	0.67
GI	Control	17	2.37	1.25	1.62	0.49	0.56	0.8	-0.15	-0.01	0.96	0.31	0,95	0.002*
	Test	17	2.52	1.27	0.66	0.42	0.79	0.66
PPD	Control	17	8.12	5.88	4.94	1.22	1.11	0.66	-0.41	0.23	0.59	0.19	0.04*	0.001*
	Test	17	8.53	5.65	4.35	1.5	1.11	0.61
CAL	Control	17	7.82	6.35	5.12	2.6	1.84	0.93	-0.41	1.06	0.88	0.31	0.003*	0.001*
	Test	17	8.24	5.29	4.24	3.27	1.57	0.83
Defect Depth	Control	17	67.63	56.57	39.5	25.64	24.54	20.43	-10.9	10.64	11.33	0.08	0.02*	0.009*
	Test	17	78.53	45.93	28.17	38.76	23.53	15.76
Defect Filling	Control	17	-	19.15	45.2	-	13.98	15.95	-	-22.51	-18.33	-	0.001*	<0.001*
	Test	17	-	41.66	63.52	-	13.9	14.86

*- Statistically Significant; PI,GI-scores; PPD, CAL, DD – mm; DF - %