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. 2024 Jun 26;183(9):3943–3958. doi: 10.1007/s00431-024-05639-8

Table 2.

Analysis of Rome III Diagnostic Questionnaire for the Pediatric Functional GI Disorders in the control group pre- and post-pharmaceutical treatment

Variables Pre-treatment
(n = 200)
Post-treatment
(n = 200)
Test of significance
1. In the last 2 months, how often did you usually have poops?
 ▪ 2 times a week or less often 180 160

MC = 14.51

P = 0.001*

 ▪ 3 to 6 times a week 20 28
 ▪ Once a day 0 (0%) 12
 ▪ 2 to 3 times a day 0 (0%) 0 (0%)
 ▪ More than 3 times a day 0 (0%) 0 (0%)
2. In the last 2 months, what was your poop usually like?
 ▪ Very hard 132 116

MC = 35.166

P < 0.001*

 ▪ Hard 68 52
 ▪ Not too hard and not too soft 0 (0%) 16
 ▪ Very soft or mushy 0 (0%) 0 (0%)
 ▪ Watery 0 (0%) 0 (0%)
 ▪ It depends (my poops are not always the same) 0 (0%) 16 (8%)
2a. If your poops were usually hard, for how long have they been hard?
 ▪ Less than 1 month 0 (0%) 8

MC = 9.40

P = 0.009

 ▪ 1 month 112 92
 ▪ 2 months 88 84
 ▪ 3 or more months 0 (0%) 0 (0%)
3. In the last 2 months, did it hurt when you had a poop?
 ▪ No 80 80

χ2 = 0

P = 1

 ▪ Yes 120 120
4. Did you have to rush to the bath-room to poop?
 ▪ Never 0 (0%) 52

MC = 213.07

P < 0.001*

 ▪ Once in a while 0 (0%) 84
 ▪ Sometimes 20 16
 ▪ Most of the time 112 32
 ▪ Always 68 16
5. Did you have to strain (push hard) to make a poop come out?
 ▪ Never 0 (0%) 4

MC = 98.11

P < 0.001*

 ▪ Once in a while 0 (0%) 72 (36%)
 ▪ Sometimes 20 20 (10%)
 ▪ Most of the time 112 56
 ▪ Always 68 48
6. Did you pass mucus or phlegm (white, yellowish, stringy, or slimy material) during a poop?
 ▪ Never 0 (0%) 20 (10%)

MC = 221.03

P < 0.001*

 ▪ Once in a while 0 (0%) 112
 ▪ Sometimes 20 (10%) 24 (12%)
 ▪ Most of the time 112 16 (8%)
 ▪ Always 68 28 (14%)
7. Did you have a feeling of not being finished after a poop (like there was more that wouldn’t come out)?
 ▪ Never 0 (0%) 8 (4%)

MC = 103.81

P < 0.001*

 ▪ Once in a while 0 (0%) 72 (36%)
 ▪ Sometimes 20 (10%) 20 (10%)
 ▪ Most of the time 112 56 (28%)
 ▪ Always 68 44 (22%)
8. In the last 2 months, did you have a poop that was so big that it clogged the toilet?
 ▪ No 16 (8%) 60 (30%)

χ2 = 31.44

P < 0.001*

 ▪ Yes 184 (92%) 140 (70%)
9. Some children hold in their poop even when there is a toilet they could use. They may do this by stiffening their bodies or crossing their legs. In the last 2 months, while at home, how often did you try to hold in a poop?
 ▪ Never 36 (18%) 36 (18%)

MC = 4.57

P = 0.33

 ▪ 1 to 3 times a month 68 (34%) 68 (34%)
 ▪ Once a week 48 (24%) 36 (18%)
 ▪ Several times a week 40 (20%) 44 (22%)
 ▪ Every day 8 (4%) 16 (8%)
10. Did a doctor or nurse ever examine you and say that you had a huge poop inside?
 ▪ No 52 (26%) 60 (30%)

χ2 = 0.794

P = 0.21

 ▪ Yes 148 (74%) 140 (70%)
11. In the last 2 months, how often was your underwear stained or soiled with poop?
 ▪ Never 0 (0%) 16 (8%)

MC = 164.40

P < 0.001*

 ▪ Less than once a month 4 (2%) 48 (24%)
 ▪ 1 to 3 times a month 12 (6%) 64 (32%)
 ▪ Once a week 56 (28%) 44 (22%)
 ▪ Several times a week 76 (38%) 28 (14%)
 ▪ Every day 52 (26%) 0 (0%)
11. a. When you stained or soiled underwear, how much was it stained or soiled?
 ▪ Underwear was stained (no poop) 76 (38%) 32 (16.9%)

MC = 42.56

P < 0.001*

 ▪ Small amount of poop in underwear (less than a whole poop) 80 (40%) 76 (38%)
 ▪ Large amount of poop in underwear (a whole poop) 44 (22%) 76 (38%)
11. b. For how long have you stained or soiled your underwear?
 ▪ 1 month or less 4 (2%) 12 (6%)

MC = 54.09

P < 0.001*

 ▪ 2 months 52 (26%) 60 (30%)
 ▪ 3 months 80 (40%) 88 (44%)
 ▪ 4 to 11 months 32 (16%) 24 (12%)
 ▪ 1 year or longer 32 (16%) 0 (0%)

Data are expressed as number (percent)

MC, Monte Carlo test; χ2, chi-square test

*Statistically significant (P < 0.05)