Table 2.

Positive MR results of the causal relationship between gut microbiota and BD risk after FDR correction.

Exposure	Taxa	Gut microbiota (outcome)	Methods	SNPs (n)	OR (95% CI)	P-value	Test of heterogeneity		Test of pleiotropy
							Cochran’s Q	P-value	Egger intercept	SE	P-value
BD	Family	Streptococcaceae	MR Egger	10	1.024(0.933–1.094)	0.569	5.046	0.753	− 0.002	0.026	0.935
			Weighted median	10	1.022(0.992–1.028)	0.015
			IVW	10	1.021(0.996–1.022)	0.002	5.053	0.830
			Simple mode	10	1.029(0.984–1.042)	0.085
			Weighted mode	10	1.025(0.983–1.04)	0.112

BD Behcet's disease, FDR False discovery rate, MR mendelian randomization, IVW inverse variance weighted, SNPs single nucleotide polymorphisms OR odds ratio, CI confidence intervals; SE: standard error.

IVW significant values are in bold.