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Schematic representation of chimeras consisting of US3 and CD4. The three letters represent the luminal, transmembrane (TM), and cytoplasmic domains, respectively, and U refers to US3, C refers to CD4, and O indicates lack of any domain. Each domain is shown as either a filled box (US3 origin) or an open box (CD4 origin). Details of the constructions are described in Materials and Methods.
