TABLE 3.
Impact of procedural and sampling variables on pneumothorax
| Variable | Pneumothorax (95% CI) | p-value, R2 analogue# |
|---|---|---|
| 2.4 mm versus 1.9 mm size of cryoprobe | 0.11 (0.08–0.15) versus 0.01 (0.00–0.01) | p<0.00001 |
| Routine post-procedure imaging versus no routine imaging | 0.07 (0.06–0.08) versus 0.02 (0.02–0.03) | p<0.00001 |
| One or more mean lobes versus single lobe | 0.09 (0.07–0.11) versus 0.03 (0.01–0.05) | p<0.0001 |
| Reduced mean DLCO | Coefficient −0.0025 (−0.0047– −0.0003) | p=0.028, R2=0.17 |
| GA versus sedation | 0.06 (0.05–0.07) versus 0.05 (0.04–0.06) | p=0.05 |
| Increasing mean age | Coefficient 0.0015 (0.0003–0.0027) | p=0.013, R2=0.0 |
| Higher mean FVC | Coefficient 0.0036 (0.0012–0.006) | p=0.0031, R2=0.0 |
| No lobes targeted versus lower lobes targeted | 0.05 (0.04–0.06) versus 0.04 (0.03–0.06) | p=0.39 |
| Mean number of biopsies | Coefficient 0.0008 (−0.011–0.013) | p=0.89, R2=0.0 |
| No imaging guidance versus fluoroscopy (sole imaging guidance) | 0.08 (0.04–0.11) versus 0.07 (0.06–0.08) | p=0.89 |
#: Reported for meta-regression analyses. DLCO: diffusing capacity for carbon monoxide; FVC: forced vital capacity; GA: general anaesthesia.