Figure 3.
Transgene expression can be modulated via virus-hydrogel incubation time and PLL concentration. (A) PEG hydrogels functionalized with 2.5 mM RGD and 0.45 mg/mL of PLL were incubated with virus for varying times (n = 3). Fold increase in GLuc expression relative to RGD control. Significant difference compared to RGD control (**P ≤ 0.01; ***P ≤ 0.001). (B) Hydrogels were functionalized with varied concentrations of PLL and incubated with virus for 3 h (n = 3). Significant difference compared to RGD control (****P ≤ 0.0001).