2.6. Analysis.
Comparison 2 Switching ‐ new antipsychotic regimen vs continuation on previous regimen: 1b. new atypical from olanzapine ‐ medium term (3‐12 months), Outcome 6 Physiological measures: 1b. Percentage changes ‐ switching to aripiprazole.
| Physiological measures: 1b. Percentage changes ‐ switching to aripiprazole | |||||
|---|---|---|---|---|---|
| Study | Group | N | % change | SE | stated p |
| lipids ‐ cholesterol | |||||
| Newcomer 2008 | Switch to aripiprazole | 80 | ‐9.5 | 1.5 | ˜0.005 |
| Newcomer 2008 | Stay on olanzapine | 76 | ‐3.3 | 1.6 | |
| lipids ‐ triglycerides | |||||
| Newcomer 2008 | Switch to aripiprazole | 54 | ‐14.46 | 4.5 (estimate from graph) | ˜0.002 |
| Newcomer 2008 | Stay on olanzapine | 61 | + 5.3 | 5.6 (estimate from graph) | |
| lipids ‐ low density lipoproteins | |||||
| Newcomer 2008 | Switch to aripiprazole | 80 | ‐11.2 | 2.5 | ˜0.072 |
| Newcomer 2008 | Stay on olanzapine | 76 | ‐4.7 | 2.7 | |
| lipids ‐ high density lipoproteins | |||||
| Newcomer 2008 | Switch to aripiprazole | 80 | +1.7 | 1.8 | ˜0.002 |
| Newcomer 2008 | Stay on olanzapine | 76 | ‐5.9 | 1.7 | |