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. Author manuscript; available in PMC: 2024 Aug 14.
Published in final edited form as: Annu Rev Pharmacol Toxicol. 2017 Jan 6;57:437–454. doi: 10.1146/annurev-pharmtox-010716-105001

Figure 1.

Figure 1

Mitochondria play vital cellular functions including oxidative phosphorylation through the Krebs cycle and the electron transport chain. Abbreviations: ADP, adenosine diphosphate; ANT, adenine nucleotide transporter; ATP, adenosine triphosphate; CoQ10, coenzyme Q 10; CytC, cytochrome C; G-6-P, glucose-6-phosphate; ETC, electron transport chain; GSH, glutathione; H2O2, hydrogen peroxide; mV, millivolt; ΔΨ, mitochondrial membrane potential; NAD+, nicotinamide adenine dinucleotide; NADP+, nicotinamide adenine dinucleotide phosphate; O2, oxygen; Pi, phosphate; PIC, phosphate channel; O2•−, superoxide anion; SOD2, superoxide dismutase 2; TRX, thioredoxin; I, complex I; II, complex II; III, complex III; IV, complex IV.