Table 1.
Demographic Characteristics of Patients With AIDS-OI (San Francisco, 1981—2012)a
| Characteristic | Patients, No. (%)b |
|||
|---|---|---|---|---|
| Pre-ART Era 1981–1986 (n = 3002) | Mono/Dual-ART Era 1987–1996 (n = 14 097) | cART Era 1997–2012 (n = 3759) | Total 1981–2012 (N = 20 858) | |
|
| ||||
| Age at AIDS-OI diagnosis, y | ||||
| 13–35 | 1268 (42.2) | 4691 (33.3) | 780 (20.8) | 6739 (32.3) |
| 36–45 | 1209 (40.3) | 6228 (44.2) | 1572 (41.8) | 9009 (43.2) |
| ≥46 | 525 (17.5) | 3178 (22.5) | 1407 (37.4) | 5110 (24.5) |
| Race/ethnicity | ||||
| Hispanic | 245 (8.2) | 1612 (11.4) | 629 (16.7) | 2486 (11.9) |
| Black, non-Hispanic | 166 (5.5) | 1625 (11.5) | 755 (20.1) | 2546 (12.2) |
| White, non-Hispanic | 2559 (85.3) | 10 665 (75.7) | 2171 (57.8) | 15 395 (73.8) |
| Other | 32 (1.1) | 195 (1.4) | 204 (5.4) | 431 (2.1) |
| Sex at birth | ||||
| Male | 2983 (99.4) | 13 685 (97.1) | 3453 (91.9) | 20 121 (96.5) |
| HIV transmission category | ||||
| MSM | 2485 (82.8) | 10 844 (76.9) | 2241 (59.6) | 15 570 (74.7) |
| IDU | 32 (1.1) | 876 (6.2) | 519 (13.8) | 1427 (6.8) |
| MSM and IDU | 448 (14.9) | 2102 (14.9) | 798 (21.2) | 3348 (16.1) |
| Heterosexual with HIV-infected or IDU/MSM sex partner | 11 (0.37) | 126 (0.89) | 129 (3.4) | 266 (1.3) |
| Other/unknown | 26 (0.87) | 149 (1.1) | 72 (1.9) | 247 (1.2) |
| Multiple first AIDS-OIs | 317 (10.6) | 1754 (12.4) | 376 (10.0) | 2447 (11.7) |
| Follow-up time, median (range) y | 1.00 (<1.0 to 29.3) | 1.52 (<1.0 to 25.5) | 5.16 (<1.0 to 15.6) | 1.6 (<1.0 to 29.3) |
| Vital status | ||||
| Dead | 2955 (98.4) | 12 569 (89.2) | 1573 (41.9) | 17 097 (82.0) |
| AIDS-OI mentioned on death certificate (n = 17 097) | 1660 (56.2) | 9335 (74.3) | 1160 (73.7) | 12 155 (71.1) |
Abbreviations: AIDS-OI, AIDS-defining opportunistic illness; ART, antiretroviral therapy; cART, combination ART; HIV, human immunodeficiency virus; IDU, injection drug user; MSM, men who have sex with men.
a
Patients had a total of 3411, 16 206, and 4190 first AIDS-OIs across the 3 treatment eras, respectively (some had multiple first AIDS-OIs). All characteristics were determined at the time of first AIDS-OI diagnosis, unless otherwise specified.
b
Data represent No. (%) of patients unless otherwise noted.