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. 2024 Jul 2;15(8):e01316-24. doi: 10.1128/mbio.01316-24

Fig 7.

An illustration highlights fold changes in gene expression of MTTP, APOB, and LCT from RNA sequening analysis and bar graphs plotting relative expression levels measured by RT-qPCR in infants and adult enteroid monolayers.

Lactase and lipid metabolism genes are significantly upregulated in infant HIEs. (A) Expression profile of RNA-seq data for lactase and lipid metabolism genes. (B–D) RT-qPCR data for (B) microsomal triglyceride transfer protein (MTTP), (C) apolipoprotein B (APOB), and (D) lactase (LCT) transcripts. Data represent mean ± SD from two independent experiments, with each experiment including the three infant and three adult HIE lines. The P-values were calculated by student’s t-test and the asterisks (*** and ****) represent P < 0.001 and P < 0.0001, respectively.