FIG. 1.
Location of ORF S/L in the VZV genome. (A) Schematic representation of the linear VZV genome. The repeat sequences TRL/IRL (■) and IRS/TRS (░⃞) are depicted. The four overlapping cosmids are indicated relative to their map positions beneath the genomic diagram. (B) The VZV genome is circularized by adjoining TRL and TRS and accounting for the one unpaired nucleotide. The region of the genome near the TRL/TRS junction is expanded to show the presence of ORFs and selected restriction sites in both Dumas and Oka. The ORF 1 and ORF 2 designations are consistent with those of Davison and Scott (12). ORF S/L Dumas and ORF S/L Oka initiate at different positions.