Fig. 4.

Relationships between SOX4 expression and markers of different subsets immune cells in GEPIA. (A–G) The plots show the association between SOX4 expression in hepatocellular carcinoma (HCC) and markers from tumor-infiltrating monocytes (CD86) (A), neutrophils (CCR7 and ITGAM) (B, C), Th2 cells (STAT6) (D), natural killer (NK) cells (KIR3DL1, XCL1, CD7) (E–G), tumor-associated macrophages (TAMs; IL-10 and CD68) (H, I), Tregs (CCR8, STAT5B, and TGFB1) (J–L), Th1 cells (STAT1, IFNG, TBX21, and TNF) (M-P), and exhausted T cells (LAG3, PDCD1, CTLA4, and HAVCR2) (Q-T) in HCC. TAMs, NK cells, Th1 cells, follicular helper T (Tfh) cells, and Tregs. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001