Fig. 7.

Identification of hsa-miR-204-5p as a potential miRNA upstream of SOX4 in hepatocellular carcinoma (HCC). (A–E) Expression of LINC00472 (A), MCM3AP-AS1 (B), NEAT1 (C), KCNQ1OT1 (D), and MALAT1 (E) in HCC and control samples, as determined using the UALCAN database. (F) Correlation of predicted lncRNA expression and SOX4 expression in HCC, as analyzed using the R software package ‘ggstatsplot’ with a dataset comprised of mRNA-seq data for HCC from The Cancer Genome Atlas. (G–K) The prognostic significance of high or low MCM3AP-AS1, NEAT1, KCNQ1OT1, MALAT1, and LINC00472 expression in HCC, as analyzed using starBase. (L) Correlation between predicted MCM3AP-AS1 expression and hsa-miR-204-5p expression in HCC, as analyzed using starBase. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, NC: not significant