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. 2024 Aug 14;25:641. doi: 10.1186/s12891-024-07729-y

Table 1.

Characteristics of OA patients, stratified by cardiovascular health status

Variables Total (n = 1676) Groups p
Low CVH n = 301 (17.9%) Moderate CVH n = 1136 (67.8%) High CVH n = 239 (14.3%)
Age, years, mean (S.E) 60.3 (0.3) 58.9 (0.8) 60.7 (0.4) 59.7 (0.9) 0.126a
Gender, n (%) 0.217b
 Female 1068 (65.2) 206 (71.4) 700 (63.5) 162 (66.6)
Race/Ethnicity, n (%)  < 0.001b***
 Mexican American 132 (3) 23 (4) 101 (3.3) 8 (1.2)
 Non-Hispanic Black 239 (5.6) 64 (10.6) 160 (5.6) 15 (1.9)
 Non-Hispanic White 1045 (82.7) 172 (76.3) 693 (81.9) 180 (90.2)
 Other Hispanic 123 (2.6) 17 (2.1) 89 (2.7) 17 (2.3)
 Other race-including multi-racial 137 (6.1) 25 (7) 93 (6.5) 19 (4.4)
Education Level, n (%)  < 0.001b***
 Less than 9th Grade 111 (3) 35 (7.2) 69 (2.6) 7 (1.5)
 9-11th Grade-including 12th grade with no diploma 187 (8.1) 62 (18) 120 (7.9) 5 (1.4)
 High school Grade/GED or Equivalent 346 (19.8) 70 (26.6) 240 (21.2) 36 (10.4)
 Some College or Arts degree 555 (33.5) 111 (41.2) 395 (35.4) 49 (21)
 College Graduate or above 477 (35.6) 23 (7) 312 (32.9) 142 (65.7)
PIR, n (%)  < 0.001b***
 ≤ 1.85 616 (25.1) 168 (46.7) 403 (24.8) 45 (10.4)
 > 1.85 944 (68.9) 108 (44.3) 656 (69.5) 180 (84.7)
 Unknown 116 (6) 25 (9) 77 (5.7) 14 (4.9)
Marital Status, n (%) 0.005b**
 Married 1001 (66.4) 152 (57.4) 679 (66.2) 170 (73.7)
Drinking alcohol, n (%) 0.543b
 Yes 1490 (91.1) 272 (92.4) 1009 (91.3) 209 (89.2)
Duration of OA, mean (SE) 11.73 (0.35) 11.94 (0.81) 12.21 (0.46) 9.93 (0.83) 0.068a
Fracture, n (%) 0.214b
 No 788 (45.4) 133 (45.5) 538 (45.1) 117 (46.6)
 Yes 205 (12.2) 39 (14) 150 (13.4) 16 (6.6)
 Unknown 683 (42.4) 129 (40.5) 448 (41.5) 106 (46.8)
CVD, n (%)  < 0.001b***
 Yes 338 (17.2) 86 (29.4) 233 (17.8) 19 (6.2)
Cancer, n (%) 0.889b
 Yes 332 (22.7) 53 (22.8) 223 (23) 56 (21.4)
White blood cell count, 1000 cells/uL, mean (SE) 7.2 (0.1) 8.2 (0.2) 7.3 (0.1) 6.3 (0.2)  < 0.001a***
Energy, kcal, mean (SE) 1975.19 (27.79) 1900.05 (70.42) 1977.40 (33.51) 2022.25 (54.23) 0.371a
Drug for OA, n (%) 0.005b**
 Yes 30 (1.4) 9 (3.6) 19 (1.1) 2 (0.7)
All-cause mortality, n (%)  < 0.001b***
 Alive 1457 (90.4) 245 (84.7) 992 (90.5) 220 (94.3)
 Dead 219 (9.4) 56 (15.3) 144 (9.5) 19 (5.7)
Survival time, month, mean (SE) 66.9 (1.7) 67.0 (2.9) 66.7 (2.0) 67.4 (3.1) 0.980a

SE standard error, PIR poverty-to-income ratio, GED general equivalent diploma, AA Associate of Arts, CVD cardiovascular disease, LE8 Life’s Essential 8, CVH cardiovascular health, OA osteoarthritis

aF test with P > 0.05, a*: F test with P < 0.05, a**: F test with P < 0.01, a***: F test with P < 0.001

bChi-square test with P > 0.05, b*: Chi-square test with P < 0.05, b**: Chi-square test with P < 0.01, b***: Chi-square test with P < 0.001