Table 3.
Subgroup analysis of association between the moderate-to-high cardiovascular health and all-cause mortality risk in patients with osteoarthritis duration and the presence or absence of cardiovascular diseases
| Subgroup | Alive/Dead (n) | HR (95% CI) | p |
|---|---|---|---|
| Duration of OA < 5 years | 445/60 | ||
| Groups | |||
| Low CVH | 74/13 | Ref | |
| Moderate CVH | 287/42 | 0.93 (0.47—1.81) | 0.825 |
| High CVH | 84/5 | 0.64 (0.19–2.15) | 0.465 |
| Per 10 points increase | 0.89 (0.69–1.15) | 0.379 | |
| Duration of OA ≥ 5 years | 1012/159 | ||
| Groups | |||
| Low CVH | 171/43 | Ref | |
| Moderate CVH | 705/102 | 0.57 (0.37–0.88) | 0.012 |
| High CVH | 136/14 | 0.41 (0.21–0.82) | 0.011 |
| Per 10 points increase | 0.79 (0.71–0.87) | < 0.001 | |
| CVD | 257/81 | ||
| Groups | |||
| Low CVH | 56/30 | Ref | |
| Moderate CVH | 188/45 | 0.63 (0.32–1.25) | 0.186 |
| High CVH | 13/6 | 0.53 (0.13–2.15) | 0.364 |
| Per 10 points increase | 0.81 (0.68–0.97) | 0.019 | |
| No CVD | 1200/138 | ||
| Groups | |||
| Low CVH | 189/26 | Ref | |
| Moderate CVH | 804/99 | 0.65 (0.41–1.02) | 0.062 |
| High CVH | 207/13 | 0.42 (0.22–0.80) | 0.009 |
| Per 10 points increase | 0.80 (0.69—0.92) | 0.002 | |
OA osteoarthritis, HR hazard ratio, CI confidence interval, Ref reference, CVH cardiovascular health
If not stratified, adjusted for age, education level, PIR, marital status, Duration of OA, fracture, CVD, cancer, WBC, and energy