Table 1.
Multivariate analysis of AUC values (panel miRNA – sample - disease interaction model with healthy control groups)
| Coefficient | Estimate | SE | t-stat | d.f. (Satt) | p-val (Satt) | Sig. |
|---|---|---|---|---|---|---|
| Reference | 0.84 | 0.02 | 34.95 | 16.67 | < 0.001 | *** |
| Sample: Urine | 0.05 | 0.03 | 2.05 | 18.05 | 0.06 | . |
| Disease: Focal segmental glomerulosclerosis | -0.07 | 0.05 | -1.41 | 6.27 | 0.21 | |
| Disease: Lupus nephritis | -0.03 | 0.03 | -0.83 | 19.92 | 0.42 | |
| Disease: membranous nephropathy | -0.06 | 0.06 | -1.12 | 4.39 | 0.32 | |
| Disease: IgA nephropathy | -0.08 | 0.05 | -1.85 | 9.3 | 0.10 | . |
| Panel miRNA | 0.08 | 0.02 | 4.61 | 8.88 | 0.001 | ** |
Legend: contains the multivariate analysis of the panel – sample type - disease interaction in the model with healthy control groups. The reference variables were diabetic nephropathy (DN) – sample type: blood - single miRNAs. Significance: p < 0.001***, p < 0.01**, p > 0.05*.