FIG 2.

Comparison of microbiota β-diversity visualized by the PCoA plot and α-diversity estimated by observed richness and Shannon diversity between children with allergic rhinitis and non-rhinitis controls in the (A) overall group (N = 273; case/control = 99/174), (B) biparental atopy (N = 106; case/control = 47/59), (C) non-biparental atopy (N = 167; case/control = 52/115) sub-group. ns, non-significant. (D) top 15 abundant bacterial genera identified in the non-biparental atopy sub-group. The genera significantly enriched (positive coefficients) or depleted (negative coefficients) in children with rhinitis after controlling for other early-life factors are in bold (see Table S2F for full results).