Aβ aggregation inhibitory activities of coumarin triazolyl and phenoxyphenyl triazolyl derivatives.

Compound	R1	X	R2	IC50 (μM) ±SD
CA1		–NH–		a
CA2		–NH–		a
CA3		–NH–		11.58 ± 1.26
CA4		–NH–		a
CA5		–NH–		a
CE1		–O–		a
CE2		–O–		a
CE3		–O–		17.66 ± 5.12
CE4		–O–		a
CE5		–O–		0.008 ± 5.91
PA1		–NH–		a
PA2		–NH–		a
PA3		–NH–		69.20 ± 0.99
PA4		–NH–		1.15 ± 1.24
PA5		–NH–		0.04 ± 1.61
PE1		–O–		4.73 ± 2.53
PE2		–O–		a
PE3		–O–		36.66 ± 0.89
PE4		–O–		0.003 ± 0.66
PE5		–O–		14.13 ± 6.11
Curcumin				20.34 ± 1.87

^aExhibiting inhibitory activity below 50%.