In vitro evaluation of the synthesized molecules.

Compound	R	IC50 α-glucosidase (μM)	IC50 α-amylase (μM)
9A	–CH2Ph	31.20 ± 0.012	55.58 ± 0.016
9B	4-MePhCH2–	20.31 ± 0.147	54.24 ± 0.083
9C	3-NO2PhCH2–	99.10 ± 0.026	64.77 ± 0.014
9D	4-NO2PhCH2–	38.33 ± 0.311	93.53 ± 0.089
9E	4-ClPhCH2–	96.15 ± 0.129	125.77 ± 0.089
9F	Allyl bromide	9.8 ± 0.047	17.10 ± 0.015
9G	Propargyl bromide	5.15 ± 0.017	9.2 ± 0.092
9H	4-Me-PhSO2–	42.24 ± 0.010	48.72 ± 0.086
9I	4-FPhCH2–	46.51 ± 0.096	60.10 ± 0.0163
11A	H	58.44 ± 0.075	43.99 ± 0.014
11B	5-Cl	53.18 ± 0.174	50.76 ± 0.012
11C	5-Br	68.76 ± 0.558	60.99 ± 0.011
Acarbose	—	25.33 ± 1.25 (ref. 50)	22.57 ± 2.30 (ref. 50)