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. 2024 Aug 2;18(8):e0012377. doi: 10.1371/journal.pntd.0012377

Table 11. Reported cases of organ transplant-donor derived human ehrlichiosis (n = 7).

No. Year of publication Age of patient (years) Sex of patient Country of infection Pre-existing medical conditions Organ transplantation due to Culprit transplant organ Time between transplantation and onset of symptoms (days) Diagnosis of human ehrlichiosis established by Ehrlichia species Antimicrobial therapy Time between onset of fever and appropriate treatment (days) Complications Outcome Ref.
1 2014 57 Female USA ESRD secondary to hypertension, HCV, GERD ESRD Kidney 22 PCR, serology E. chaffeensis Doxycycline 5 N.r. N.r. [18]
2 2014 56 Male USA HTN, HCV, sleep apnea, HTN Kidney 25 Serology E. chaffeensis Tigecycline 12 Renal failure, DIC, spontaneous hemorrhage Survived [18]
3 2021 70 Male USA ESRD from polycystic kidney disease ESRD Kidney 17 PCR, microscopy E. chaffeensis Doxycycline 7 HLH, seizure, E. coli septicemia, DVT, candida fungemia Died [17]
4 2021 66 Male USA ESRD due to DM2, nephrectomy for renal cell carcinoma, adult onset Still disease ESRD, renal cell carcinoma Kidney 9 PCR E. chaffeensis N.r. N.r. HLH, cardiac arrest Died [17]
5 2021 5 Male USA ESRD due to obstructive uropathy ESRD Kidney 9 PCR N.r. Doxycycline 7 N.r. Survived [17]
6 2021 6 Male USA ESRD due to obstructive uropathy ESRD Kidney 9 PCR E. chaffeensis Doxycycline 9 HLH Survived [17]
7 2021 69 Male USA HCV-related cirrhosis HCV-related cirrhosis Liver 11 PCR N.r Doxycycline 1 N.r. Survived [17]

DIC, disseminated intravascular coagulopathy; DM2, diabetes mellitus type 2; E. coli, Escherichia coli; E. chaffeensis, Ehrlichia chaffeensis; ESRD, end-stage renal disease; DVT, deep vein thrombosis; GERD, gastroesophageal reflux disease; HCV, hepatitis C virus; HLH, hemophagocytic lymphohistiocytosis; HTN, hypertensive nephropathy; N.r., none/not reported; PCR, polymerase chain reaction; Ref., reference; USA, United States of America.