Comparison of bacterial Shannon diversity in skin microbiomes of participants with rosacea (A) before treatment (baseline) and after treatment with E-BPO or (B) E-BPO and vehicle cream at Week 8/Visit 6 (intent-to-treat population). Box plot illustrating the comparison of bacterial Shannon alpha diversity in skin microbiomes of E-BPO cream, 5%, and vehicle cream–treated participants at Week 8. The line in the box is a median of index scores, the boxes represent the interquartile range, the whiskers represent the lowest and highest values, and the dots represent outliers. Wilcoxon rank sum test was performed.
E-BPO: microencapsulated benzoyl peroxide cream, 5%; ns: not significant