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. 2024 Aug;17(8):56–61.

TABLE 2.

Laboratory tests susceptible to biotin interference38,39

POSITIVE INTERFERENCE (FALSELY ELEVATED) NEGATIVE INTERFERENCE (FALSELY DIMINISHED)
Aldosterone ACTH, FSH, HGH, LH, PTH, SHBG, TSH
Androstenedione AFP
Anti-HAV Total Anti-CCP
Anti-TSH receptor Anti-HAV IgM
Anti-TPO Anti-HBc IgM & HBsAg
Anti-Thyroglobulin (both) Anti-HCV
Cortisol Calcitonin & Procalcitonin
Cyclosporine Cancer Ags (125, 15-3, 19-9, CEA, HE4, PSA)
DHEAS Cardiac biomarkers (Troponin, CK-MB, Myoglobin)
Digoxin
Estradiol EPO
Folate Ferritin
FT3, FT4, T3, T4 Gastrin
Progesterone HIV 1/2 Ag/Ab [41]
Testosterone [40] Insulin, IGF-1, C-peptide
Vitamin B12 IgE
Vitamin D Total NT-proBNP
17-OH-progesterone Prolactin
25-Hydroxyvitamin D Qualitative hCG [42]