Table 1.
Ablation zone measurements as identified in tissue cross sections on gross slab section examination and CT imaginga
| Tissue cross section | CT imaging | Route, tunnel length | Pig, lobe location | ||||||
|---|---|---|---|---|---|---|---|---|---|
| W | H | AR [–] | W1 | W2 | H | AR [–] | |||
| W1 | W2 | ||||||||
| 90 W, 5 min | |||||||||
| 2.4b | 3.2 | 0.75 | 3.1 | 3.3 | 4.1 | 0.77 | EB | Pig 2, right superior | |
| 2.1 | 3.4 | 0.65 | 3.0 | 3.2 | 4.1 | 0.76 | TB, 3 cm | Pig 2, left inferior | |
| 1.6 | 3.7 | 0.43 | 2.1 | 2.6 | 4.7 | 0.50 | TB, 3 cm | Pig 2, left middle | |
| 2.0±0.3 | 3.4±0.2 | 0.6±0.2 | min 2.7±0.4 | 4.3±0.3 | 0.7±0.2 | ||||
| max 3±0.3 | |||||||||
| all 2.9±0.4 | |||||||||
| 120 W, 10 min | |||||||||
| 2.7b | 3.2 | – | – | 3.8 | 4.2 | 5.1 | 0.78 | EB | Pig 2, right middle |
| 3.5 | 5.2 | 0.67 | 3.5 | 4.2 | 4.8 | 0.80 | TB, 4 cm | Pig 1, left superior | |
| 2.4c | 2.5 | – | – | 3.3 | 3.5 | 5.3 | 0.64 | EB | Pig 1, left inferior |
| 2.1d | 2.9 | – | – | 2.6 | 2.6 | 3.2 | 0.81 | EB | Pig 1, right inferior |
| 3.1±0.4 | 5.2 | 0.67 | min 3.3±0.4 | 4.6±0.8 | 0.8±0 | ||||
| max 3.6±0.6 | |||||||||
| all 3.5±0.6 | |||||||||
| 60 W, 5 min (from Sebek et al. [19], presented for comparison) | |||||||||
| min 1.1±0.3 | – | – | min 1.7±0.4 | 2.6±0.4 | 0.80 | ||||
| max 1.3±0.1 | max 2.4±0.5 | ||||||||
All dimensions are in cm, except for axial ratio (AR), which is dimensionless.
EB, endobronchial; TB, transbronchial.
aOnly W1 and W2, or W and H could be measured on gross tissue cross sections, depending on the orientation of the section relative to the ablation catheter insertion (see Fig. 3).
bCT image shown in Figure 6.
cAblation stopped after 4 min 20 s, device handle over-heated; not accounted for in summary statistics.
dAblation stopped after 8 min 48 s, device leak observed, dimension W1 affected by lung boundary and not accounted for in summary statistics.