Table 4.

Cytotoxic activities of compounds 2 and 3 against five human tumor cell lines

Compound	HL-60	A-549	SMMC-7721	MDA-MB-231	SW-480
2	1.65 ± 0.02	3.23 ± 0.14	1.27 ± 0.08	1.99 ± 0.05	2.51 ± 0.14
3	2.76 ± 0.18	7.52 ± 0.33	4.13 ± 0.09	5.43 ± 0.11	4.48 ± 0.11
Paclitaxel	< 0.008	< 0.008	0.095 ± 0.007	< 0.008	< 0.008
Cisplatin	2.92 ± 0.15	11.95 ± 0.25	20.52 ± 0.63	19.28 ± 0.30	21.32 ± 1.05

Results are expressed as IC₅₀ values in μM. Cisplatin and paclitaxel were used as positive controls