Table 2.

Potential confounders in cases of haemorrhage (a) and hypotension (b)

(a)
Haemorrhage
Enoxaparin ± clopidogrel
Variable		AEs of interest	Other AEs	P value
Lorazepam	No, n (%)	104 (100)	142 (85.0)
	Yes, n (%)	0 (0)	25 (9.2)	0.001
Age	Mean (SD)	73.8 (9.7)	71.9 (11.2)	0.161

(b)
Hypotension
Bisoprolol ± alfuzosin					Bisoprolol ± doxazosin
Variable		AEs of interest	Other AEs	P value	Variable		AEs of interest	Other AEs	P value
Apixaban	No, n (%)	13 (100)	9 (47)		Acetylsalicylic Acid	No, n (%)	33 (100)	51 (87)
	Yes, n (%)	0 (0)	10 (53)	0.006		Yes, n (%)	0 (0)	8 (13)	0.068
Carbidopa/levodopa	No, n (%)	9 (69)	19 (100)		Cefalexin	No, n (%)	33 (100)	52 (88)
	Yes, n (%)	4 (31)	0 (0)	0.041		Yes, n (%)	0 (0)	7 (12)	0.099
Cefuroxime	No, n (%)	13 (100)	9 (47)		Naproxen	No, n (%)	33 (100)	52 (88)
	Yes, n (%)	0 (0)	10 (53)	0.005		Yes, n (%)	0 (0)	7 (12)	0.099
Dutasteride	No, n (%)	9 (69)	19 (100)		Warfarin	No, n (%)	33 (100)	47 (80)
	Yes, n (%)	4 (31)	0 (0)	0.041		Yes, n (%)	0 (0)	12 (20)	0.014
Ezetimibe	No, n (%)	13 (100)	9 (47)		Age	Mean (SD)	54.7 (23.5)	66.5 (20.4)	0.011
	Yes, n (%)	0 (0)	10 (53)	0.005
Furosemide	No, n (%)	13 (100)	17 (89)
	Yes, n (%)	0 (0)	2 (11)	0.642
Glyburide/Metformin	No, n (%)	13 (100)	17 (89)
	Yes, n (%)	0 (0)	2 (11)	0.642
Hydrochlorothiazide /Olmesartan	No, n (%)	13 (100)	17 (89)
	Yes, n (%)	0 (0)	2 (11)	0.642

Chi-square test for categorical variables and t test or Wilcoxon rank-sum test based on parametric assumptions for continuous variables were used to test significant difference between groups

AE adverse event