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. 2024 Aug 14;9:148. doi: 10.1038/s41541-024-00931-y

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

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Fig. 3 — Fc-mediated functions of anti-NP and anti-GP38 antibodies were investigated after first and second vaccinations. ADCD function of anti-NP A and anti-GP38 C antibodies are represented as the fold change in complement deposition over mock-vaccinated group. ADCP function of anti-NP B and anti-GP38 D antibodies represented as fold change in phagocytic score over mock-vaccinated animals. Each dot represents the mean value of the replicates from each animal and the horizontal line represents the median. Two-tailed nonparametric t tests and ordinary one-way ANOVA (*p < 0.05; **p < 0.001; ***p < 0.0003) were used for statistical analyses when applicable. Statistical analyses compare vaccine groups and mock-vaccinated animals at corresponding timepoints.