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. 2024 Jun 15;23(8):100803. doi: 10.1016/j.mcpro.2024.100803

Fig. 3.

Fig. 3

Chondroitin sulfate (CS) disaccharides analysis for lateral hypothalamus (LH).A, absolute abundance in fmol for four CS disaccharides (D0a0, D2a4, D0a6, and D0a10) for saline (blue color), cocaine (red color), and METH (green color) in LH. B, relative abundance (%) for 4-0 sulfation (4S) and 6-0 sulfation (6S) for saline-, cocaine-, and METH-treated samples in LH. C, Total CS abundance in fmol for saline-, cocaine-, and METH-treated samples in LH. D, sulfate content (%) for saline-, cocaine-, and METH-treated samples in LH. (∗=p ≥ 0.05, ∗∗= p ≥ 0.001, ∗∗∗= p ≥ 0.0001, ∗∗∗∗= p ≥ 0.00001) (mean ± SD). E, unsupervised hierarchical clustering of the entire CS disaccharide data for saline, cocaine, and METH samples. F, heatmap representation of relative quantification for CS disaccharides (red: increased and green: decreased abundance). METH, methamphetamine.