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. 2024 Jun 18;84(16):2626–2644. doi: 10.1158/0008-5472.CAN-23-4110

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©2024 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 4. — Distribution of RI(α/β), RIIα, and C. A–C, Representative immunofluorescence images of FLC tumor and adjacent normal liver incubated with DAPI and antibody against RI (α/β) subunits (A), antibody against RIIα subunit (B), antibody against PRKACA/DNAJB::PRKACA (C). Scale bar in the left and middle column, 20 μm; right column, 5 μm. D, Quantification of PRKACA/DNAJB1::PRKACA signal in the nuclei of FLC cells (red) and adjacent normal liver tissue (blue) from three different patients. Statistics were done using two-way ANOVA in PRISM. ****, P < 0.0001.