Table 2.

Stratified analysis of pCR rate by the propensity score.

Strata	TP53 signature	n	pCR (%; 95 % CI)	Non-pCR	OR (95 % CI)	P
1	wt	66	2 (3.0; 0.2–10.9)	64	1
	mt	62	5 (8.1; 2.7–17.8)	57	2.807 (0.524–15.035)
2	wt	41	2 (4.9; 0.6–16.5)	39	1
	mt	85	22 (27.1; 17.0–36.5)	63	6.810 (1.517–30.567)
3	wt	3	0 (0.0; 0.0–70.8)	3	−
	mt	124	54 (43.5; 34.7–52.7)	70	−
Cochran-Mantel-Haenszel test					5.599(1.876–16.705)	0.0008
Breslow-Day test						0.562

Abbreviations: pCR, pathological complete response; OR, odds ratio; CI, confidence interval; wt, wild-type; mt, mutant.