Table 2.
Unadjusted and Adjusted PR for Depression Risk Factors Among People Living With HIV in a Single Center in Lima, Peru (N = 139).
| Unadjusted PR | 95% CI | P-value | Adjusted PR a |
95% CI | P-value | |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Sex | ||||||
| Male | Ref. | Ref. | ||||
| Female | 1.84 | 1.01-3.38 | .049 | 2.19 | 1.07-4.49 | .030 |
| Age (years) | ||||||
| 40-49 | Ref. | Ref. | ||||
| 50-59 | 1.01 | 0.53-1.89 | .997 | 1.24 | 0.58-2.68 | .580 |
| ≥60 | 1.16 | 0.51-2.64 | .717 | 1.58 | 0.66-3.78 | .308 |
| Educational level (years) | ||||||
| ≥12 | Ref. | NA | ||||
| <12 | 1.61 | 0.91-2.86 | .105 | |||
| Current employment type | ||||||
| Employed | Ref. | NA | ||||
| Retired | 2.36 | 1.15-4.82 | .019 | |||
| Unemployed | 1.49 | 0.76-2.89 | .242 | |||
| Civil status | ||||||
| Single | Ref. | NA | ||||
| Married or domestic partnership | 0.71 | 0.36-1.38 | .313 | |||
| Social factors | ||||||
| Alcohol use | ||||||
| No | Ref. | Ref. | ||||
| Yes | 1.30 | 0.70-2.21 | .466 | 0.96 | 0.47-1.94 | .898 |
| Current smoker | ||||||
| No | Ref. | Ref. | ||||
| Yes | 1.92 | 1.06-3.45 | .030 | 2.25 | 1.15-4.43 | .018 |
| HIV characteristics | ||||||
| Year of HIV diagnosis | 1.02 | 0.98-1.06 | .438 | 0.96 | 0.89-1.03 | .209 |
| CD4 count | ||||||
| <500 copies/mL | Ref. | Ref. | ||||
| ≥500 copies/mL | 1.80 | 0.90-3.57 | .099 | 1.69 | 0.82-3.50 | .155 |
| Plasma HIV viral load | ||||||
| Undetectable | Ref. | Ref. | ||||
| Detectable | 1.22 | 0.54-2.76 | .628 | 1.76 | 0.66-4.70 | .258 |
| Prior non-CNS opportunistic infection b | ||||||
| No | Ref. | Ref. | ||||
| Yes | 1.73 | 0.98-3.05 | .057 | 2.24 | 1.05-4.76 | .037 |
| Efavirenz, current use | ||||||
| No | Ref. | Ref. | ||||
| Yes | 0.63 | 0.36-1.11 | .115 | 0.38 | 0.16-090 | .027 |
| Adherence to ART | ||||||
| No | Ref. | Ref. | ||||
| Yes | 0.55 | 0.31-0.99 | .050 | 0.79 | 0.36-1.72 | .547 |
a
Multivariable analyses were adjusted for the following covariates: sex, age, current alcohol use, current smoker, years with HIV diagnosis, current absolute CD4 count, plasma HIV viral load, prior opportunistic infection, current efavirenz use, adherence to ART.
b
Prior opportunistic infection included any history of: candidiasis, Kaposi's sarcoma, cytomegalovirus, or pneumocystis pneumonia.
Abbreviations: 95% CI, 95% confidence interval; ART, antiretroviral treatment; CNS, central nervous system; PR, prevalence ratio; Ref., reference; SD, standard deviation.
Bold text, P < .05 (significant).