Fig. 5.

Dot plot showing top enriched pathways from GSEA for neuronal (A) and non-neuronal (B) cell clusters. Red and blue indicate higher and lower pathway activities, in the numeric form of normalized enrichment scores (NES), in the CHD8 KO samples compared to controls, respectively. Dot sizes indicate statistical significance defined as 1/FDR. A full version is shown in Supplementary Fig. 4. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)