Table 1. Median Inhibitory Concentration (IC50) and Average IC50 (GI50) of Each Compound against the Four Cancer Cell Lines.
comp | cell viability % | cytotoxic
activity IC50 ± SEM (nM) |
||||
---|---|---|---|---|---|---|
A-549 | MCF-7 | Panc-1 | HT-29 | average (GI50) | ||
4 | 91 | 47 ± 4 | 50 ± 5 | 48 ± 4 | 49 ± 4 | 49 |
5 | 89 | 67 ± 6 | 71 ± 6 | 68 ± 6 | 70 ± 6 | 68 |
6 | 90 | 42 ± 4 | 46 ± 4 | 44 ± 4 | 47 ± 4 | 45 |
7 | 93 | 70 ± 7 | 74 ± 7 | 72 ± 7 | 73 ± 7 | 71 |
8 | 92 | 64 ± 6 | 68 ± 6 | 67 ± 6 | 68 ± 6 | 67 |
9 | 90 | 74 ± 7 | 79 ± 7 | 75 ± 7 | 77 ± 7 | 76 |
10 | 89 | 52 ± 5 | 55 ± 5 | 52 ± 5 | 54 ± 5 | 53 |
11 | 92 | 56 ± 5 | 58 ± 5 | 56 ± 5 | 59 ± 5 | 57 |
12 | 87 | 36 ± 3 | 38 ± 3 | 36 ± 3 | 38 ± 3 | 37 |
13 | 90 | 62 ± 6 | 64 ± 6 | 61 ± 6 | 64 ± 6 | 62 |
14 | 89 | 40 ± 4 | 44 ± 4 | 42 ± 4 | 43 ± 4 | 41 |
15 | 91 | 33 ± 3 | 36 ± 3 | 34 ± 3 | 36 ± 3 | 35 |
erlotinib | ND | 30 ± 3 | 40 ± 3 | 30 ± 3 | 30 ± 3 | 33 |