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| compound | EGFR inhibition IC50 ± SEM (nM) | VEGFR-2 inhibition IC50 ± SEM (nM) |
|---|---|---|
| 6 | 98 ± 6 | 5.30 ± 0.050 |
| 12 | 87 ± 5 | 4.20 ± 0.040 |
| 14 | 92 ± 5 | 4.70 ± 0.040 |
| 15 | 84 ± 5 | 3.50 ± 0.030 |
| erlotinib | 80 ± 5 | |
| sorafenib | 0.17 ± 0.001 |
