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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: Am J Obstet Gynecol MFM. 2023 Oct 22;5(12):101200. doi: 10.1016/j.ajogmf.2023.101200

Table 6.

Interaction between treatment type (GPNC versus IPNC) and race and ethnicity for serum inflammatory markers and placental inflammation

Modified Intent-to-Treat (mITT) Median or more visits in assigned treatment group (M+)

Estimate (95% CL) p-value Estimate (95% CL) p-value

Composite inflammatory score in 2nd trimester Black
Hispanic/Latine
White
−0.15 (−0.95 – 0.66)
0.06 (−0.94 – 1.06)
−0.42 (−1.24 – 0.41)
0.72
0.91
0.32
0.08 (−0.99 – 1.15)
0.26 (−0.89 – 1.41)
−0.10 (−1.12 – 0.93)
0.88
0.66
0.85

Composite inflammatory score in 3rd trimester Black
Hispanic/Latine
White
0.19 (−0.52 – 0.91)
1.17 (0.31 – 2.03)
0.15 (−0.57 – 0.86)
0.59
0.01
0.68
−0.20 (−1.11 – 0.71)
1.24 (0.24 – 2.24)
0.02 (−0.88 – 0.92)
0.66
0.02
0.96

aOR (95% CL) p-value aOR (95% CL) p-value

Maternal Acute or Chronic Inflammatory
Lesions
Black
Hispanic/Latine
White
1.22 (0.75 – 2.00)
1.14 (0.61 – 2.11)
1.35 (0.86 – 2.11)
0.43
0.68
0.19
1.30 (0.70 – 2.41)
1.31 (0.62 – 2.79)
1.35 (0.79 – 2.32)
0.41
0.49
0.27

Adjusted for age, BMI, smoking before pregnancy, GA at blood draw

Bolded results indicate p<0.05