Table 6.
Interaction between treatment type (GPNC versus IPNC) and race and ethnicity for serum inflammatory markers and placental inflammation
| Modified Intent-to-Treat (mITT) | Median or more visits in assigned treatment group (M+) | ||||
|---|---|---|---|---|---|
|
| |||||
| Estimate (95% CL) | p-value | Estimate (95% CL) | p-value | ||
|
| |||||
| Composite inflammatory score in 2nd trimester | Black Hispanic/Latine White |
−0.15 (−0.95 – 0.66) 0.06 (−0.94 – 1.06) −0.42 (−1.24 – 0.41) |
0.72 0.91 0.32 |
0.08 (−0.99 – 1.15) 0.26 (−0.89 – 1.41) −0.10 (−1.12 – 0.93) |
0.88 0.66 0.85 |
|
| |||||
| Composite inflammatory score in 3rd trimester | Black Hispanic/Latine White |
0.19 (−0.52 – 0.91) 1.17 (0.31 – 2.03) 0.15 (−0.57 – 0.86) |
0.59 0.01 0.68 |
−0.20 (−1.11 – 0.71) 1.24 (0.24 – 2.24) 0.02 (−0.88 – 0.92) |
0.66 0.02 0.96 |
|
| |||||
| aOR (95% CL) | p-value | aOR (95% CL) | p-value | ||
|
| |||||
|
Maternal Acute or Chronic Inflammatory
Lesions |
Black Hispanic/Latine White |
1.22 (0.75 – 2.00) 1.14 (0.61 – 2.11) 1.35 (0.86 – 2.11) |
0.43 0.68 0.19 |
1.30 (0.70 – 2.41) 1.31 (0.62 – 2.79) 1.35 (0.79 – 2.32) |
0.41 0.49 0.27 |
Adjusted for age, BMI, smoking before pregnancy, GA at blood draw
Bolded results indicate p<0.05