Table 3. ANOVA for Response Surface Polynomial Model of All Independent Variable^a.

	Yield (%)		DPPH (%)		ABTS (%)		TPC(mg/g)		TFC (mg QAE/g DW)
Source	F-value	p-value	F-value	p-value	F-value	p-value	F-value	p-value	F-value	p-value
Model	34.54	<0.0001	51.1	<0.0001	20.36	<0.0001	151.73	<0.0001	217.1	<0.0001
X1-Rising Time	0.0802	0.7808	0.714	0.4114	1.62	0.2222	6.03	0.0268	11.48	0.0041
X2-Temp	136.87	<0.0001	93.9	<0.0001	14.16	0.0019	5.52	0.0329	386.93	<0.0001
X3-L/S	10.99	0.0047	12.9	0.0027	3.42	0.0843	6.42	0.0229	35.96	<0.0001
X4-Holding Time	32.69	<0.0001	129.93	<0.0001	41.57	<0.0001	181.01	<0.0001	4.47	0.0517
X1X2	27.72	<0.0001	0.0316	0.8613	0.9746	0.3392	29.6	<0.0001	8.78	0.0097
X1X3	20.75	0.0004	0.2406	0.6308	1.26	0.2796	1.89	0.1891	1.46	0.2463
X1X4	2.47	0.1366	0.1509	0.7031	1.72	0.2099	0.7178	0.4102	10.21	0.006
X2X3	35.76	<0.0001	73.66	<0.0001	12.76	0.0028	94.95	<0.0001	7.44	0.0156
X2X4	20.20	0.0004	12.5	0.003	19.17	0.0005	72.73	<0.0001	6.58	0.0215
X3X4	8.07	0.0124	4.56	0.0497	8.01	0.0127	41.01	<0.0001	3.03	0.1021
X12	0.0347	0.8547	8.59	0.0103	10.59	0.0053	41.44	<0.0001	223.67	<0.0001
X22	54.90	<0.0001	11.9	0.0036	7.22	0.0169	565.47	<0.0001	589.37	<0.0001
X32	2.62	0.1265	5.04	0.0403	0.0081	0.9297	45.66	<0.0001	22.98	0.0002
X42	5.53	0.0328	88.91	<0.0001	64.41	<0.0001	0.6226	0.4424	13.02	0.0026
LOF	0.716	0.6953	3.01	0.118	0.7785	0.6568	0.7876	0.6513	2.94	0.1231
CV%	3.57		5.56		7.51		2.65		3.05
PRESS	57.3		712.37		912.01		124.9		147.86
R2	0.97		0.9795		0.95		0.993		0.9951
Adjusted R2	0.94		0.9603		0.90		0.986		0.9905
Predicted R2	0.91		0.9042		0.87		0.975		0.9813
Adeq Precision	23.2		23.587		15.45		39.56		42.7768
AAD	0.585		1.9		2.521		0.833		0.83
MSE	0.618		5.1		12.84		1.151		1.29
RSME	0.786		2.3		3.582		1.073		1.14
MPE	0.018		0.1		0.171		0.017		0.02

^aLOF: Lack of Fit; CV: Coefficients of variation; AAD: average absolute deviation; MSE: mean square error; RSME: root-mean-square error; MPE: mean percentage error.