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. 2024 Jul 20;5(3):103202. doi: 10.1016/j.xpro.2024.103202

Figure 5.

Figure 5

Expected outcomes of CTV labeling in PDX-ALL cells, MS40, after co-culture with MSCs

(A) The dot plot displaying the retention of CTV dye in PDX-ALL cells immediately after CTV dye labeling (day 0).

(B) The dot plot displaying retention of CTV dye in untreated PDX-ALL cells after 5 days.

(C) The dot plot displaying retention of CTV dye in PDX-ALL cells treated with dexamethasone (10 nM) after 5 days.

(D) Overlay histogram for untreated day 0 (blue), untreated day 5 (black) and dexamethasone treated day 5 (red) patient-derived cells. Peaks shown further right on the histogram have retained a higher level of CTV dye indicating these cells have cycled slower, compared to peaks more to the left on the histogram which have retained less dye and cycled faster.