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Boxplots of whole-exome sequencing derived genomic features for A) SBS18+SBS36 proportions in MUTYH cases and non-hereditary groups and B) SBS30 proportions in NTHL1 cases and non-hereditary groups.
Abbreviations: MMR, DNA mismatch repair; SBS, single base substitution; CRC,colorectal cancer; VUS, variant of uncertain significance; LP, likely pathogenic.
