Table 2.

Metabolite levels association with IDS-SR30 total scores and with symptom profiles.

Metabolite		Estimate	SE	P	q
C2	Total IDS-SR30	−0.03	0.02	8.10e−2	2.16e−1
	AES	−0.05	0.02	1.85e−2	7.40e−2
	Anhedonic	−0.01	0.02	4.99e−1	7.26e−1
	Melancholic	−0.01	0.02	4.77e−1	7.26e−1
C3	Total IDS-SR30	0.06	0.02	1.20e−3	9.60e−3
	AES	0.08	0.02	3.42e−5	5.47e−4
	Anhedonic	0.05	0.02	5.80e−3	3.09e−2
	Melancholic	0.03	0.02	7.67e−2	2.16e−1
C8	Total IDS-SR30	−0.001	0.02	9.48e−1	9.48e−1
	AES	−0.02	0.02	2.33e−1	4.66e−1
	Anhedonic	−0.002	0.02	9.35e−1	9.48e−1
	Melancholic	0.01	0.02	5.89e−1	7.85e−1
C10	Total IDS-SR30	−0.002	0.02	9.26e−1	9.48e−1
	AES	−0.03	0.02	1.30e−1	2.97e−1
	Anhedonic	0.01	0.02	7.40e−1	9.11e−1
	Melancholic	0.02	0.02	3.00e−1	5.33e−1

Covariates – shipment, age, sex, education. SE, Standard error; P, level of significance; AES, atypical energy-related symptoms; q, Adjusted P-levels obtained by BH-FDR (Benjamini-Hochberg False Discovery Rate) correction, used to control the rate of false positives in multiple testing.