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. 2024 Aug 15;19(8):e0308948. doi: 10.1371/journal.pone.0308948

Table 1. Patient demographics of the study cohort and differences between high adherence (HAG) and low adherence group (LAG).

All patients QI adherence groups*
HAG LAG
n = 20220 n = 4879 n = 15341
Demographics 
Age in years a 64.6 (36.9) 64.1 (22.8) 64.8 (22.0)
Male sex (%) 11780 (58.3) 2954 (60.5) 8826 (57.5)
Admission type (%)
    Elective surgery 7159 (35.4) 2437 (49.9) 4722 (30.8)
    Emergency surgery 4349 (21.5) 908 (18.6) 3441 (22.4)
    Medical 8712 (43.1) 1534 (31.4) 7178 (46.8)
Score on admission
    APACHE II  15 [10;22] 14 [9;22] 15 [10;21]
    SAPS II  34 [24;49] 34 [24;50] 35 [24;48]
    CCI (age-adjusted) 5 [3;8] 5 [3;7] 5 [3;8]
Adherence to quality indicator
QI overall 0.79 [0.63;0.89] 0.94 [0.92;0.99] 0.73 [0.56;0.81]
QI sedation  0.81 [0.63;0.92] 0.97 [0.90;1.0] 0.75 [0.50;0.85]
QI pain  0.81 [0.67;0.91] 0.97 [0.91;1.0] 0.75 [0.58;0.83]
QI delirium  0.78 [0.57;0.90] 1.00 [0.91;1.0] 0.70 [0.5;0.82]
Outcome parameter
Patients with MV (%)** 14637 (72,4%) 3698 (75,8%) 10939 (71,3%)
Duration of MV (hours) 45 [12;163] 34 [11;95] 51 [12;196]
LOS study ICU 3.7 [1.9;8.0] 3.6 [1.8;6.6] 3.8 [1.9;9.0]
LOS hospital  14 [8;23] 13 [8;20] 14 [8;24]
Death ICU  2024 (10%) 351 (7.2%) 1673 (10.9%)
Death hospital  2590 (12.8%) 448 (9.2%) 2142 (14.0%)
Readmission hospital 725 (3.6%) 543 (3.5%) 182 (3.7%)
Economic outcomes
DRG income (in €)  17080 [8503;32397] 17348 [10156;27942] 17010 [8156;33133]
Total costs (in €)  17815 [10477;30657] 16820 [11349;25624] 18415 [10208;32536]
Revenue margin (in €)  -320 [-3928;4840] 197 [-3236;5277] -482 [-4193;4679]

*threshold value ≥ 8/9

**patients with at least 1 hour of mechanical ventilation (MV); percent of complete cohort or respective adherence group; All values presented as median with interquartile range, except where indicated. aMean value with standard deviation; SAPS = Simplified Acute Physiologic Score; CCI = Charlson Comorbidity Index. DRG = Diagnosis related groups.