Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Dec 7;230(2):e447–e456. doi: 10.1093/infdis/jiad564

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — Positivity for differentially detectable/culturable Mycobacterium tuberculosis (DD Mtb) at week 2 (as determined by the most probable number from the liquid limiting dilution assay performed with culture filtrate [MPN^+CF] to colony-forming units [CFU] ratio) is associated with a slower rate of Mtb killing during the first 2 weeks of therapy as determined by the maximum Mtb count (Mtb^Max) obtained by CFU, MPN^−CF, or MPN^+CF (A). A similar trend is observed by time to positivity (TTP) by BACTEC MGIT (B). Top panels show data per subject, middle panels show median values per cohort ± 95% confidence intervals, and bottom panels show box plots for the reduction in Mtb counts during the first 2 weeks of therapy based on DD Mtb status.