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. 2024 Jul 14;43:103641. doi: 10.1016/j.nicl.2024.103641

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© 2024 The Authors

This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Fig. 1 — MEGA-PRESS spectra. Panel (a) depicts a heat plot of the MRS voxels in the left thalamus and medial prefrontal cortex. This plot was generated by normalizing all anatomical T1 scans to standard stereotactic space and calculating the overlap of regions of interest between subjects. Panel (b) depicts the standard deviations (shaded area) and the mean spectra of PD group. Abbreviations: HC = healthy control; NDPD = nondepressed Parkinson’s disease; DPD = depression in Parkinson’s disease; GABA = γ-aminobutyric acid; Glx = glutamate plus glutamine.