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. 2024 Jul 14;43:103641. doi: 10.1016/j.nicl.2024.103641

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© 2024 The Authors

This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Fig. 2 — Metabolites, including GABA+, change in Parkinson’s disease (PD), demonstrating the GABA+, Glx, NAA, and Cho levels in patients with PD and healthy controls. Only the levels of NAA/Cr and Cho/Cr in the left thalamus were significantly lower in patients with PD than in HC (P = .031, P = .009); others had no difference. Abbreviations: GABA = γ-aminobutyric acid; Glx = glutamate plus glutamine; Cr = creatine; NAA = N-acetyl aspartate; Cho = Choline; MFC = medial prefrontal cortex; HC = healthy controls; PD = Parkinson's disease.