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. 2024 Aug 2;14:1410656. doi: 10.3389/fonc.2024.1410656

Table 1.

Diagnostic and prognostic microRNAs.

MicroRNA Sample source Expression Function Target Implication Reference
MiR-16 Bone marrow Upregulated Tumor suppressor VEGF Prognosis (13)
MiR-22 Bone marrow/Plasma Upregulated Role in HSC renewal TET2 Prognosis (14)
MiR-146b Bone marrow Upregulated Role in tumorigenesis, erythropoiesis, megakaryopoiesis TRAF6, IRAK1, PDGFRA Diagnostic and prognostic marker (15, 16)
MiR-181 Bone marrow Upregulated Regulator of granulocytic and macrophage differentiation PRKCD, CTDSPL, CAMKK1 Prognostic marker (7, 17, 18)
MiR-320 Bone marrow Upregulated Diagnostic and prognostic marker (4, 19)
MiR-424 Bone marrow Downregulated Regulator of monocyte and macrophage differentiation VEGFR2 Diagnostic marker, therapy response marker (15, 20, 21)
MiRs in DLK1-DIO3 genomic region Bone marrow Upregulated Apoptosis, regulation of HSPC differentiation MEG3-DMR Prognostic markers, Therapy response markers (22)
MiR-194 Bone marrow Upregulated Apoptosis p53 Prognostic marker (4)
MiR-218 Downregulated Role in tumorigenesis SLIT2/3 Prognostic marker, Potential therapeutic target (23)