Table 1.
MicroRNA | Sample source | Expression | Function | Target | Implication | Reference |
---|---|---|---|---|---|---|
MiR-16 | Bone marrow | Upregulated | Tumor suppressor | VEGF | Prognosis | (13) |
MiR-22 | Bone marrow/Plasma | Upregulated | Role in HSC renewal | TET2 | Prognosis | (14) |
MiR-146b | Bone marrow | Upregulated | Role in tumorigenesis, erythropoiesis, megakaryopoiesis | TRAF6, IRAK1, PDGFRA | Diagnostic and prognostic marker | (15, 16) |
MiR-181 | Bone marrow | Upregulated | Regulator of granulocytic and macrophage differentiation | PRKCD, CTDSPL, CAMKK1 | Prognostic marker | (7, 17, 18) |
MiR-320 | Bone marrow | Upregulated | Diagnostic and prognostic marker | (4, 19) | ||
MiR-424 | Bone marrow | Downregulated | Regulator of monocyte and macrophage differentiation | VEGFR2 | Diagnostic marker, therapy response marker | (15, 20, 21) |
MiRs in DLK1-DIO3 genomic region | Bone marrow | Upregulated | Apoptosis, regulation of HSPC differentiation | MEG3-DMR | Prognostic markers, Therapy response markers | (22) |
MiR-194 | Bone marrow | Upregulated | Apoptosis | p53 | Prognostic marker | (4) |
MiR-218 | Downregulated | Role in tumorigenesis | SLIT2/3 | Prognostic marker, Potential therapeutic target | (23) |